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Hemophilia A

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Jesse's Story

Read Jesse's story Competitive baseball player with hemophilia mentors kids with bleeding disorders.

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Novel Recombinant Hemophilia Treatments

CSL Behring’s recombinant factor development pipeline is built on its strength in protein research and development and scientific expertise in bleeding disorders

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Hemophilia A is the most common type of hemophilia, comprising about 80% of hemophilia cases. In two-thirds of cases, hemophilia A is an inherited bleeding disorder and the disposition is known (positive family history). The other one-third of cases are due to new mutations, where the family history will be negative.

Symptoms of Hemophilia A

People born with hemophilia A are usually males, because the gene is located on the X-chromosome. Females have two X-chromosomes, one of which is usually a healthy X-chromosome, which compensates for a potentially defective Factor VIII (FVIII) gene on the other (this makes them carriers of hemophilia A). This is not the case in males, who have an X- and a Y-chromosome.

The symptoms of hemophilia A may vary from occasional to frequent spontaneous bleedings. Acquired hemophilia A occurs when non-hemophiliacs form antibodies against FVIII. Triggers for acquired hemophilia A may include pregnancy or other medical conditions.

The most common hemophilia A symptoms are:
  • Bruising easily (for example, an infant born with hemophilia A may bruise simply from being lifted.)
  • Bleeding in the mouth from a cut or bite or from losing a tooth
  • Bleeding into joints (tightness, swelling, warmth and/or pain in the joints)
  • Bleeding into soft tissues
  • Heavy bleeding from a minor cut
  • Cuts that bleed again after they have already stopped for a short time
  • Blood in the urine or stool, resulting from bleeding in internal organs

Tim’s Video Story – Outdoor Adventurer Living With Hemophilia

For information about hemophilia A treatment options, please visit the following resources:

Not all products are available in every country. To learn what products are available in your country, visit your CSL Behring country site.

Find out more about Haemophilia

Last Updated: 6/15/2016 8:41 AM
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