Inherited bleeding disorders may range in intensity from mild to very severe. In a person with a severe bleeding disorder, clotting factors in the blood might be deficient or completely dysfunctional/defective. These individuals may seem to bleed without pause, or can experience lengthy, heavy bleeding with a minor injury.
About 80% of all people with hemophilia have hemophilia A, which is caused by a deficiency of the plasma protein called clotting factor VIII (FVIII). Hemophilia B results from the deficiency of another plasma protein: factor IX (FIX). One or more defects in the genetic coding for von Willebrand factor (VWF) are apparent in nearly 1% of the background population, but more than 90% are generally asymptomatic. Other rare disorders do exist, including platelet dysfunctions, and deficiencies of clotting factors I, II, V, VII, X, XI and XIII, which are necessary for coagulation.
View these hereditary bleeding disorders to understand the common symptoms:
12/30/2014 5:16 PM