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All About Bleeding
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Hemophilia B (Christmas Disease)

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Hemophilia B, also known as Christmas disease, is the second most common type of hemophilia, affecting about 20% of people with hemophilia. It is typically an inherited bleeding disorder that results from a deficiency of Factor IX.

Symptoms of Hemophilia B

Like hemophilia A, people born with hemophilia B are usually male, because the gene is located on the X-chromosome. Females have two X-chromosomes, one of which is usually a healthy X-chromosome, which compensates for a potentially defective Factor IX gene on the other (this makes them carriers of hemophilia B). This is not the case in males, who have an X- and a Y-chromosome. The symptoms of hemophilia B (Christmas Disease) may vary from almost none to frequent spontaneous bleedings.

The most common symptoms of hemophilia B are:
  • Bruising easily (for example, an infant born with hemophilia B may bruise simply from being lifted)
  • Bleeding in the mouth from a cut or bite or from losing a tooth
  • Bleeding into joints (tightness, swelling, warmth and/or pain in the joints
  • Bleeding into soft tissues
  • Heavy bleeding from a minor cut
  • Cuts that bleed again after they have already stopped for a short time
  • Blood in the urine or stool, resulting from bleeding in internal organs
Learn more about treatment options for hemophilia B:

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Last Updated: 4/14/2016 11:37 AM
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