Hemophilia B, also known as Christmas disease, is the second most common type of hemophilia, affecting about 20% of people with hemophilia. It is typically an inherited bleeding disorder that results from a deficiency of Factor IX.
Symptoms of Hemophilia B
Like hemophilia A, people born with hemophilia B are usually male, because the gene is located on the X-chromosome. Females have two X-chromosomes, one of which is usually a healthy X-chromosome, which compensates for a potentially defective Factor IX gene on the other (this makes them carriers of hemophilia B). This is not the case in males, who have an X- and a Y-chromosome. The symptoms of hemophilia B (Christmas Disease) may vary from almost none to frequent spontaneous bleedings.
The most common symptoms of hemophilia B are:
Learn more about treatment options for hemophilia B:
- Bruising easily (for example, an infant born with hemophilia B may bruise simply from being lifted)
- Bleeding in the mouth from a cut or bite or from losing a tooth
- Bleeding into joints (tightness, swelling, warmth and/or pain in the joints
- Bleeding into soft tissues
- Heavy bleeding from a minor cut
- Cuts that bleed again after they have already stopped for a short time
- Blood in the urine or stool, resulting from bleeding in internal organs
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