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Hemophilia B

Understanding Bleeding

Learn the basics about blood and blood clotting.

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Hemophilia B, also known as Christmas disease, is the second most common type of hemophilia, affecting about 15% of people with hemophilia. It is typically an inherited bleeding disorder that results from a deficiency of Factor IX.

Symptoms of Hemophilia B

Like hemophilia A, people born with hemophilia B are usually male, because the gene is located on the X-chromosome. Females have two X-chromosomes, one of which is usually a healthy X-chromosome, which compensates for a potentially defective Factor VIII gene on the other (this makes them carriers of hemophilia B). This is not the case in males, who have an X- and a Y-chromosome. The symptoms of hemophilia B may vary from almost none to frequent spontaneous bleedings.

The most common symptoms of
Hemophilia B are:

  • Bruising easily (for example, an infant born with hemophilia B may bruise simply from being lifted)
  • Bleeding in the mouth from a cut or bite or from losing a tooth
  • Heavy nosebleeds (epistaxis) for no obvious reason
  • Heavy bleeding from a minor cut
  • Cuts that bleed again after they have already stopped for a short time
  • Blood in the urine or stool, resulting from bleeding in internal organs
  • Tightness, swelling, warmth and/or pain in the joints
Learn more at SignsOfBleeding.com

Learn more about a treatment option for hemophilia B:

Not all products are available in every country. To learn what products are available in your country, visit your CSL Behring country site.

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