Perioperative bleeding depends on the extent and complexity of the surgical procedure and on the patient’s coagulation status. It can be classified as surgical or coagulopathic bleeding, but is often due to a combination of the two.
- Surgical bleeding is excessive bleeding from vessels at the operative site, with no bleeding from other sites.
- Coagulopathic bleeding occurs as a result of a coagulopathy (e.g. reduced fibrinogen (factor I), consumption of coagulation factors and platelets, or excessive breakdown of cross-linked fibrin in clots (fibrinolysis)). It develops early after surgical trauma and is characterized by slower 'oozing' at the operative site and petechiae, purpura, or bleeding at other sites.22-23
Patients Likely to Be at Risk
Unexpected and massive bleeding can complicate any surgical procedure, leading to a significant increase in perioperative mortality. Patients considered to be more likely to experience excessive bleeding include:
- Those with advanced liver disease
- Patients undergoing high-risk surgical procedures (e.g. trauma, cardiac/cardiovascular and cancer surgery)
- High-risk obstetric patients
- Patients suffering major trauma
- Patients with underlying bleeding disorders.24-25
If you would like to learn more about perioperative bleeding and recent advances to treatment, please visit perioperativebleeding.org.
CSL Behring's products used in the treatment of perioperative bleeding include:
Not all products are available in every country. To learn what products are available in your country, visit your CSL Behring country site.
11/7/2014 2:36 PM